I've been using "NIC Padlock" to remotely disable network cards. Actually, the program lets you disable a NIC for a certain period of time (or for good). I've been using this tool to disable an office user's network cards for 2-4 hours when they are suspected to have malicious activity. That gives my techs time to physically reach the user and remediate the problem, while keeping the user from possibly infecting other systems or leaking data.
Disabling Internet Access
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